5  Secondary APL

• ~10% of the newly diagnosed APL cases
• Prospective study by the French–Belgian–Swiss APL group, Braun et al. (2015), confirmed that patients with sAPL have clinical features and outcomes (CR rate, cumulative incidence of relapse, and OS rate) similar to those of patients with de novo APL.

Braun, Thorsten, Sophie Cereja, Sylvie Chevret, et al. 2015. “Evolving Characteristics and Outcome of Secondary Acute Promyelocytic Leukemia (APL): A Prospective Analysis by the French-Belgian-Swiss APL Group.” Cancer 121 (14): 2393–99. https://doi.org/10.1002/cncr.29389.